Dickopff 1 inhibits cancer stem cell properties and promotes neuronal differentiation of human neuroblastoma cell line SH-SY5Y

Neuroblastomas are pediatric tumors arising from undifferentiated cells of neural crest origin with stem cell-like characteristics. Dysregulation of Wnt/β-catenin signaling has been shown to be linked to the development of various tumors. Activated Wnt signaling results in β-catenin accumulation in...

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Bibliographic Details

Published in:	IBRO Neuroscience Reports
Main Authors:	Shubham Krishna, Bharat Prajapati, Pankaj Seth, Subrata Sinha
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Subjects:	Neuroblastoma DKK1 Wnt signaling SH-SY5Y cancer stem cell SH-SY5Y differentiation
Online Access:	http://www.sciencedirect.com/science/article/pii/S2667242124000551