Why don't CD8+ T cells reduce the lifespan of SIV-infected cells in vivo?

In January 2010 two groups independently published the observation that the depletion of CD8+ cells in SIV-infected macaques had no detectable impact on the lifespan of productively infected cells. This unexpected observation led the authors to suggest that CD8+ T cells control SIV viraemia via non-...

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出版年:	PLoS Computational Biology
主要な著者:	Marjet Elemans, Nafisa-Katrin Seich Al Basatena, Nichole R Klatt, Christos Gkekas, Guido Silvestri, Becca Asquith
フォーマット:	論文
言語:	英語
出版事項:	Public Library of Science (PLoS) 2011-09-01
オンライン･アクセス:	https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1002200&type=printable