Impact of donor CYP3A5 genotype on pharmacokinetics of tacrolimus in South African paediatric liver transplant patients

Background. In the paediatric liver transplant programme in Johannesburg, South Africa (SA), tacrolimus is the calcineurin inhibitor of choice, comprising an essential component of the immunosuppression regimen. It is characterised by a narrow therapeutic index and wide interpatient variability...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:South African Medical Journal
المؤلفون الرئيسيون: C Wheeler, C Masimirembwa, B Mthembu, J Botha, J Scholefield, J Fabian
التنسيق: مقال
اللغة:الإنجليزية
منشور في: South African Medical Association 2024-04-01
الموضوعات:
Tacrolimus
CYP3A5
Paediatric
Liver Transplant
Living Donor
Pharmacogenetics
الوصول للمادة أونلاين:https://samajournals.co.za/index.php/samj/article/view/1367

الانترنت

https://samajournals.co.za/index.php/samj/article/view/1367

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