Pathological and clinical insights into DICER1 hotspot mutated Sertoli-Leydig cell tumors: a comparative analysis

Abstract Background Sertoli-Leydig cell tumors (SLCTs) are a rare group of sex cord-stromal tumors that account for less than 0.5% of all ovarian tumors. This study aims to compare the pathological and clinical characteristics of SLCTs with and without DICER1 hotspot mutations, highlighting the impa...

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Bibliographic Details

Published in:	Diagnostic Pathology
Main Authors:	Zhuoyao Lyu, Yilin Liu, Jingci Chen, Pengyan Wang, Zhaohui Lu, Xiaoyan Chang, Xianlong Chen, Heng Ma, Shengwei Mo, Shuangni Yu, Jie Chen
Format:	Article
Language:	English
Published:	BMC 2025-04-01
Subjects:	Sertoli-Leydig cell tumors DICER1 RNase IIIb hotspot mutations Clinical features Pathological characteristics
Online Access:	https://doi.org/10.1186/s13000-025-01657-8