Sodium-Dependent Glucose Transporter-2 Inhibitor Enhances the Hypotensive Effect of Renal Denervation by Inhibiting Sympathetic Activity and Inflammatory Reaction

Background: Sodium-dependent glucose transporter-2 inhibitors (SGLT-2i) have potential hypotensive effects, enhancing the hypotensive effect of renal denervation (RDN). Spontaneously hypertensive rats (SHRs) were used to verify this hypothesis and explore the associated underlying...

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Bibliographic Details

Published in:	Frontiers in Bioscience-Landmark
Main Authors:	Hao Zhang, Zhuqing Li, Wei Cai, Yanxin Wang, Jiaxin Feng, Xuemei Yin, Qi Li, Ning Yang, Chengzhi Lu, Yuming Li
Format:	Article
Language:	English
Published:	IMR Press 2025-06-01
Subjects:	sodium-dependent glucose transporter-2 inhibitor blood pressure renal denervation inflammation hypertension
Online Access:	https://www.imrpress.com/journal/FBL/30/6/10.31083/FBL31309