Transfer RNA-Derived Fragments and isomiRs Are Novel Components of Chronic TBI-Induced Neuropathology

Neuroinflammation is a secondary injury mechanism that evolves in the brain for months after traumatic brain injury (TBI). We hypothesized that an altered small non-coding RNA (sncRNA) signature plays a key role in modulating post-TBI secondary injury and neuroinflammation. At 3threemonths post-TBI,...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Noora Puhakka, Shalini Das Gupta, Niina Vuokila, Asla Pitkänen
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Subjects:	TBI tRNA miRNA isomiR neuroinflammation RNAseq
Online Access:	https://www.mdpi.com/2227-9059/10/1/136