Bacillus Calmette-Guérin immunotherapy induces an efficient antitumor response to control murine melanoma depending on MyD88 signaling

Bacillus Calmette-Guérin (BCG) is the first line treatment for bladder cancer and it is also proposed for melanoma immunotherapy. BCG modulates the tumor microenvironment (TME) inducing an antitumor effective response, but the immune mechanisms involved still poorly understood. The immune profile of...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Vinícius M. Borges, Fábio V. Marinho, Christiane V. A. Caldeira, Nina M. G. P. de Queiroz, Sergio C. Oliveira
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-05-01
Subjects:	Bacillus Calmette-Guérin (BCG) cancer immunotherapy melanoma innate immune pathways MyD88 TLRs
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1380069/full