Enrichment of trimethyl histone 3 lysine 4 in the Dlk1 and Grb10 genes affects pregnancy outcomes due to dietary manipulation of excess folic acid and low vitamin B12

Abstract The aberrant expression of placental imprinted genes due to epigenetic alterations during pregnancy can impact fetal development. We investigated the impact of dietary modification of low vitamin B12 with varying doses of folic acid on the epigenetic control of imprinted genes and fetal dev...

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Bibliographic Details

Published in:	Biological Research
Main Authors:	Divika Sapehia, Aatish Mahajan, Parampal Singh, Jyotdeep Kaur
Format:	Article
Language:	English
Published:	BMC 2024-11-01
Subjects:	Vitamin B12 Folic acid Placenta Transgenerational Histone methylation
Online Access:	https://doi.org/10.1186/s40659-024-00557-3