Exploring the Potential of Iminosugars as Antivirals for Crimean-Congo Haemorrhagic Fever Virus, Using the Surrogate Hazara Virus: Liquid-Chromatography-Based Mapping of Viral N-Glycosylation and In Vitro Antiviral Assays

Crimean-Congo haemorrhagic fever virus (CCHFV) is a pathogen of increasing public health concern, being a widely distributed arbovirus and the causative agent of the potentially fatal Crimean-Congo haemorrhagic fever. Hazara virus (HAZV) is a genetically and serologically related virus that has been...

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Bibliographic Details

Published in:	Pathogens
Main Authors:	Beatrice E. Tyrrell, Abhinav Kumar, Bevin Gangadharan, Dominic Alonzi, Juliane Brun, Michelle Hill, Tehmina Bharucha, Andrew Bosworth, Victoria Graham, Stuart Dowall, Joanna L. Miller, Nicole Zitzmann
Format:	Article
Language:	English
Published:	MDPI AG 2023-03-01
Subjects:	orthonairovirus nairovirus tick-borne virus antivirals imminosugars glycosylation
Online Access:	https://www.mdpi.com/2076-0817/12/3/399