Irregular particle morphology and membrane rupture facilitate ion gradients in the lumen of phagosomes

Localized fluxes, production, and/or degradation coupled to limited diffusion are well known to result in stable spatial concentration gradients of biomolecules in the cell. In this study, we demonstrate that this also holds true for small ions, since we found that the close membrane apposition betw...

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Bibliographic Details

Published in:	Biophysical Reports
Main Authors:	Maksim V. Baranov, Melina Ioannidis, Sami Balahsioui, Auke Boersma, Rinse de Boer, Manoj Kumar, Masato Niwa, Tasuku Hirayama, Qintian Zhou, Terrence M. Hopkins, Pieter Grijpstra, Shashi Thutupalli, Stefano Sacanna, Geert van den Bogaart
Format:	Article
Language:	English
Published:	Elsevier 2022-09-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S266707472200026X