Impaired arterial dilation and increased NOX2 generated oxidative stress in subjects with ataxia-telangiectasia mutated (ATM) kinase

Background: Subjects with mutations in the Ataxia-Telangiectasia mutated (ATM) gene encoding for ATM kinase have a greater predisposition to develop atherosclerosis, but the mechanism behind this phenomenon is not yet understood. NADPH oxidase type 2 may play a role in this process, leading to endot...

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Bibliographic Details

Published in:	Redox Biology
Main Authors:	Lorenzo Loffredo, Annarosa Soresina, Bianca Laura Cinicola, Martina Capponi, Francesca Salvatori, Simona Bartimoccia, Vittorio Picchio, Maurizio Forte, Caterina Caputi, Roberto Poscia, Vincenzo Leuzzi, Alberto Spalice, Pasquale Pignatelli, Raffaele Badolato, Marzia Duse, Francesco Violi, Roberto Carnevale, Anna Maria Zicari, Ilaria Maria Palumbo, Arianna Magna, Alessia Fallarino, Arianna Pannunzio, Enrico Maggio, Chiara Bagnato, Vittoria Cammisotto, Valentina Castellani
Format:	Article
Language:	English
Published:	Elsevier 2024-11-01
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213231724003252