Uncovering the effects of gender affirming hormone therapy on skeletal muscle and epigenetics: protocol for a prospective matched cohort study in transgender individuals (the GAME study)

Introduction Gender affirming hormone therapy (GAHT) is increasingly used by transgender individuals and leads to shifts in sex hormone levels. Skeletal muscle is highly responsive to hormone activity, with limited data on the effects of GAHT on different human tissues. Here, we present the protocol...

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Bibliographic Details

Published in:	BMJ Open
Main Authors:	Andrew Palmer, Teddy Cook, Andrew Garnham, Nir Eynon, Ariel Ginger, Sav Zwickl, Patrice R Jones, Sarah Voisin, Brendan J Nolan, Shanie Landen, Macsue Jacques, Beau Newell, Alex Wong, Javier Alvarez-Romero, Namitha Mohandas, Kirsten Seale, Ada Cheung
Format:	Article
Language:	English
Published:	BMJ Publishing Group 2022-05-01
Online Access:	https://bmjopen.bmj.com/content/12/5/e060869.full