Extracellular Vesicles from Human Cardiac Fibroblasts Modulate Calcium Cycling in Human Stem Cell-Derived Cardiomyocytes

Cardiac fibroblasts regulate the development of the adult cardiomyocyte phenotype and cardiac remodeling in disease. We investigate the role that cardiac fibroblasts-secreted extracellular vesicles (EVs) have in the modulation of cardiomyocyte Ca²⁺ cycling–a fundamental mechan...

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Bibliographic Details

Published in:	Cells
Main Authors:	Brian X. Wang, Laura Nicastro, Liam Couch, Worrapong Kit-Anan, Barrett Downing, Kenneth T. MacLeod, Cesare M. Terracciano
Format:	Article
Language:	English
Published:	MDPI AG 2022-03-01
Subjects:	fibroblast stem cell cardiomyocyte extracellular vesicles isolation ultrafiltration
Online Access:	https://www.mdpi.com/2073-4409/11/7/1171