Herpes simplex virus type I glycoprotein L evades host antiviral innate immunity by abrogating the nuclear translocation of phosphorylated NF-κB sub-unit p65

Nuclear factor (NF)-κB plays an important role in the innate immune response by inducing antiviral genes’ expression. However, the herpes simplex virus 1 (HSV-1) virus has developed multiple ways to interfere with NF-κB activity to escape the host antiviral response. Here, we found that HSV-1 envelo...

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Bibliographic Details
Published in:Frontiers in Microbiology
Main Authors: Zhaolong Li, Zhihua Feng, Zhou Fang, Jianghua Chen, Wengzhi Chen, Wangwang Liang, Qi Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
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Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1178249/full