Allele-Specific Epigenetic Regulation of <i>FURIN</i> Expression at a Coronary Artery Disease Susceptibility Locus

Genome-wide association studies have revealed an association between the genetic variant rs17514846 in the <i>FURIN</i> gene and coronary artery disease. We investigated the mechanism through which rs17514846 modulates <i>FURIN</i> expression. An analysis of isogenic monocyti...

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Bibliographic Details
Published in:Cells
Main Authors: Wei Yang, Junjun Cao, David G. McVey, Shu Ye
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Subjects:
genetic variant
genetic association
epigenetics
DNA methylation
<i>FURIN</i>
MeCP2
Online Access:https://www.mdpi.com/2073-4409/12/13/1681

Internet

https://www.mdpi.com/2073-4409/12/13/1681

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