SCA-1 Expression Level Identifies Quiescent Hematopoietic Stem and Progenitor Cells

Blood cell generation depends on continuous cellular output by the sequential hierarchy of hematopoietic stem cell (HSC) and progenitor populations that all contain quiescent and actively cycling cells. Hematopoietic stem and progenitor cells (HSPCs) express the surface molecule Stem cell antigen 1...

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Bibliographic Details

Published in:	Stem Cell Reports
Main Authors:	Mina N.F. Morcos, Kristina B. Schoedel, Anja Hoppe, Rayk Behrendt, Onur Basak, Hans C. Clevers, Axel Roers, Alexander Gerbaulet
Format:	Article
Language:	English
Published:	Elsevier 2017-06-01
Subjects:	hematopoeitic stem cells hematopoeitic progenitor cells type I interferon hematopoietic stem and progenitor cell purification and analysis hematopoietic stem and progenitor cell potential hematopoietic stem and progenitor cell heterogeneity cell cycle
Online Access:	http://www.sciencedirect.com/science/article/pii/S2213671117301662