Extended Metabolic Biosensor Design for Dynamic Pathway Regulation of Cell Factories

Summary: Transcription factor-based biosensors naturally occur in metabolic pathways to maintain cell growth and to provide a robust response to environmental fluctuations. Extended metabolic biosensors, i.e., the cascading of a bio-conversion pathway and a transcription factor (TF) responsive to th...

Full description

Bibliographic Details
Published in:iScience
Main Authors: Yadira Boada, Alejandro Vignoni, Jesús Picó, Pablo Carbonell
Format: Article
Language:English
Published: Elsevier 2020-07-01
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220304922