Development of Folate-Functionalized PEGylated Zein Nanoparticles for Ligand-Directed Delivery of Paclitaxel

In this study, we investigated the active targeted delivery of a hydrophobic drug, paclitaxel (PTX), via receptor-mediated endocytosis by folate receptors expressed on cancer cells using a protein-based nanoparticle system. PTX was loaded on zein nanoparticles and conjugated with folate (PTX/Zein-FA...

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Bibliographic Details

Published in:	Pharmaceutics
Main Authors:	Zar Chi Soe, Wenquan Ou, Milan Gautam, Kishwor Poudel, Bo Kyun Kim, Le Minh Pham, Cao Dai Phung, Jee-Heon Jeong, Sung Giu Jin, Han-Gon Choi, Sae Kwang Ku, Chul Soon Yong, Jong Oh Kim
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Subjects:	folic acid paclitaxel nanoparticle zein
Online Access:	https://www.mdpi.com/1999-4923/11/11/562