Exosome‐transmitted miR‐769‐5p confers cisplatin resistance and progression in gastric cancer by targeting CASP9 and promoting the ubiquitination degradation of p53

Abstract Background Cisplatin resistance is the main cause of poor clinical prognosis in patients with gastric cancer (GC). Yet, the exact mechanism underlying cisplatin resistance remains unclear. Recent studies have suggested that exocrine miRNAs found in the tumor microenvironment participate in...

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Bibliographic Details

Published in:	Clinical and Translational Medicine
Main Authors:	Xinming Jing, Mengyan Xie, Kun Ding, Tingting Xu, Yuan Fang, Pei Ma, Yongqian Shu
Format:	Article
Language:	English
Published:	Wiley 2022-05-01
Subjects:	CASP9 cisplatin resistance gastric cancer miR‐769‐5p p53
Online Access:	https://doi.org/10.1002/ctm2.780