Deaminative bromination, chlorination, and iodination of primary amines

Summary: The primary amino group has been seldom utilized as a transformable functionality in organic synthesis. Reported herein is a deaminative halogenation of primary amines using N-anomeric amide as the nitrogen-deletion reagent. Both aliphatic and aromatic amines are competent substrates for di...

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Bibliographic Details

Published in:	iScience
Main Authors:	Jiang-Hao Xue, Yin Li, Dong-Hang Tan, Fang-Hai Tu, Yuan Liu, Qingjiang Li, Honggen Wang
Format:	Article
Language:	English
Published:	Elsevier 2023-03-01
Subjects:	Functional group chemistry Organic chemistry Organic reaction
Online Access:	http://www.sciencedirect.com/science/article/pii/S2589004223003322