Regulation of nuclear transcription by mitochondrial RNA in endothelial cells

Chromatin-associated RNAs (caRNAs) form a relatively poorly recognized layer of the epigenome. The caRNAs reported to date are transcribed from the nuclear genome. Here, leveraging a recently developed assay for detection of caRNAs and their genomic association, we report that mitochondrial RNAs (mt...

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Bibliographic Details

Published in:	eLife
Main Authors:	Kiran Sriram, Zhijie Qi, Dongqiang Yuan, Naseeb Kaur Malhi, Xuejing Liu, Riccardo Calandrelli, Yingjun Luo, Alonso Tapia, Shengyan Jin, Ji Shi, Martha Salas, Runrui Dang, Brian Armstrong, Saul J Priceman, Ping H Wang, Jiayu Liao, Rama Natarajan, Sheng Zhong, Zhen Bouman Chen
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2024-01-01
Subjects:	mitochondrial RNA endothelial cells diabetes inflammation chromatin nucleus
Online Access:	https://elifesciences.org/articles/86204