Heparan sulphate, its derivatives and analogues share structural characteristics that can be exploited, particularly in inhibiting microbial attachment

Heparan sulphate (HS) and the related polysaccharide, heparin, exhibit conformational and charge arrangement properties, which provide a degree of redundancy allowing several seemingly distinct sequences to exhibit the same activity. This can also be mimicked by other sulphated polysaccharides, both...

Full description

Bibliographic Details

Published in:	Brazilian Journal of Medical and Biological Research
Main Authors:	T.R. Rudd, A. Hughes, J. Holman, V. Solari, E. de Oliveira Ferreira, R.M. Cavalcante Pilotto Domingues, E.A. Yates
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2012-05-01
Subjects:	Heparan sulfate Biosynthesis Structure-function Microbial attachment
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000500002