Liposomes targeting the cancer cell-exposed receptor, claudin-4, for pancreatic cancer chemotherapy

Abstract Background Claudin-4 (CLDN4), a tight junction protein, is overexpressed in several types of cancer, and is considered a biomarker for cancer-targeted treatment. CLDN4 is not exposed in normal cells, but becomes accessible in cancer cells, in which tight junctions are weakened. Notably, sur...

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Bibliographic Details

Published in:	Biomaterials Research
Main Authors:	Chaeeun Bang, Min Gyu Park, In Kyung Cho, Da-Eun Lee, Gye Lim Kim, Eun Hyang Jang, Man Kyu Shim, Hong Yeol Yoon, Sangmin Lee, Jong-Ho Kim
Format:	Article
Language:	English
Published:	American Association for the Advancement of Science (AAAS) 2023-05-01
Online Access:	https://doi.org/10.1186/s40824-023-00394-7