Antisense Oligonucleotide-mediated Knockdown in Mammary Tumor Organoids

Primary mammary tumor organoids grown in 3D are an excellent system to study tumor biology. They resemble the organization and physiology of native epithelia more closely than cancer cell lines grown in 2D, and additionally model interactions with the ECM (Boj et al., 2015; Clevers, 2016; Shamir and...

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Bibliographic Details
Published in:Bio-Protocol
Main Authors: Sarah Diermeier, David Spector
Format: Article
Language:English
Published: Bio-protocol LLC 2017-08-01
Online Access:https://bio-protocol.org/en/bpdetail?id=2511&type=0