Role of Pharmacogenetic Testing in the Risk and Safety Assessment of Valproates: The Ethnic Aspect (Review)

INTRODUCTION. Pharmacogenetic (PGx) testing plays a significant role in predicting the risk of adverse drug reactions (ADRs) associated with valproic acid (VPA) products, which are among the most prescribed medicinal products in neurology and psychiatry. However, the sensitivity and specificity of P...

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Bibliographic Details

Published in:	Безопасность и риск фармакотерапии
Main Authors:	N. A. Shnayder, V. V. Grechkina, V. V. Arkhipov, R. F. Nasyrova
Format:	Article
Language:	Russian
Published:	Ministry of Health of the Russian Federation, Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2024-07-01
Subjects:	valproic acid valproate-induced adverse reactions ethnicity genetic polymorphisms allelic variants cytochrome p450 pharmacogenetic testing pharmacogenetic panel personalised medicine
Online Access:	https://www.risksafety.ru/jour/article/view/423