Dexamethasone targeted directly to macrophages induces macrophage niches that promote erythroid expansion

Cultures of human CD34pos cells stimulated with erythroid growth factors plus dexamethasone, a model for stress erythropoiesis, generate numerous erythroid cells plus a few macrophages (approx. 3%; 3:1 positive and negative for CD169). Interactions occurring between erythroblasts and macrophages in...

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Bibliographic Details
Published in:Haematologica
Main Authors: Mario Falchi, Lilian Varricchio, Fabrizio Martelli, Francesca Masiello, Giulia Federici, Maria Zingariello, Gabriella Girelli, Carolyn Whitsett, Emanuel F. Petricoin, Søren Kragh Moestrup, Ann Zeuner, Anna Rita Migliaccio
Format: Article
Language:English
Published: Ferrata Storti Foundation 2015-02-01
Online Access:https://haematologica.org/article/view/7275