Parenteral vaccination with recombinant EtpA glycoprotein impairs enterotoxigenic E. coli colonization

ABSTRACT Enterotoxigenic E. coli (ETEC) causes hundreds of millions of cases of acute diarrheal illness in low- and middle-income regions, disproportionately in young children. To date, there is no licensed, broadly protective vaccine against these common but antigenically heterogeneous pathogens. O...

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Bibliographic Details

Published in:	Infection and Immunity
Main Authors:	Tim J. Vickers, David P. Buckley, Nazia Khatoon, Alaullah Sheikh, Bipul Setu, Zachary T. Berndsen, James M. Fleckenstein
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-06-01
Subjects:	enterotoxigenic Escherichia coli adhesins immunization heat-labile toxin diarrhea
Online Access:	https://journals.asm.org/doi/10.1128/iai.00601-24