Sele-targeted siRNA liposome nanoparticles inhibit pathological scars formation via blocking the cross-talk between monocyte and endothelial cells: a preclinical study based on a novel mice scar model

Abstract Background Pathological scars (PS) are one of the most common complications in patients with trauma and burns, leading to functional impairments and aesthetic concerns. Mechanical tension at injury sites is a crucial factor in PS formation. However, the precise mechanisms remain unclear due...

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Bibliographic Details

Published in:	Journal of Nanobiotechnology
Main Authors:	Luyu Li, Yong Wang, Jing Meng, Xue Wang, Xiaojin Wu, Yan Wo, Ying Shang, Zhen Zhang
Format:	Article
Language:	English
Published:	BMC 2024-11-01
Subjects:	Pathological scar Animal model Mechanical tension RNAi therapy Liposome nanoparticles
Online Access:	https://doi.org/10.1186/s12951-024-03003-4