Afferent input selects NMDA receptor subtype to determine the persistency of hippocampal LTP in freely behaving mice

The glutamatergic N-methyl-D-aspartate receptor (NMDAR) is critically involved in many forms of hippocampus-dependent memory that may be enabled by synaptic plasticity. Behavioral studies with NMDAR antagonists and NMDAR subunit (GluN2) mutants revealed distinct contributions from GluN2A- and GluN2B...

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Bibliographic Details

Published in:	Frontiers in Synaptic Neuroscience
Main Authors:	Jesús Javier Ballesteros, Arne Buschler, Georg Köhr, Denise Manahan-Vaughan
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2016-10-01
Subjects:	Hippocampus LTP Mouse NMDA synaptic plasticity in vivo
Online Access:	http://journal.frontiersin.org/Journal/10.3389/fnsyn.2016.00033/full