cis–trans Isomerization of silybins A and B

Methods were developed and optimized for the preparation of the 2,3-cis- and the 10,11-cis-isomers of silybin by the Lewis acid catalyzed (BF3∙OEt2) isomerization of silybins A (1a) and B (1b) (trans-isomers). The absolute configuration of all optically pure compounds was determined by using NMR and...

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Bibliographic Details
Published in:Beilstein Journal of Organic Chemistry
Main Authors: Michaela Novotná, Radek Gažák, David Biedermann, Florent Di Meo, Petr Marhol, Marek Kuzma, Lucie Bednárová, Kateřina Fuksová, Patrick Trouillas, Vladimír Křen
Format: Article
Language:English
Published: Beilstein-Institut 2014-05-01
Subjects:
2,3-cis-silybin
10,11-cis-silybin
isomerization
silibinin
silybin
silymarin
Online Access:https://doi.org/10.3762/bjoc.10.105

Internet

https://doi.org/10.3762/bjoc.10.105

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