Knockdown H19 Accelerated iPSCs Reprogramming through Epigenetic Modifications and Mesenchymal-to-Epithelial Transition

H19 is an essential imprinted gene that is expressed to govern normal embryonic development. During reprogramming, the parental pronuclei have asymmetric reprogramming capacities and the critical reprogramming factors predominantly reside in the male pronucleus. After inhibiting the expression of H1...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Ruizhen Sun, Ximei Zhang, Tiantian Gong, Yue Zhang, Qi Wang, Chenyao He, Jielan Ju, Chunmiao Jin, Wenxin Ding, Jingnan Gao, Jingling Shen, Qiuming Li, Zhiyan Shan
Format: Article
Language:English
Published: MDPI AG 2024-04-01
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Online Access:https://www.mdpi.com/2218-273X/14/5/509