Suprachiasmatic nucleus dysfunction induces anxiety- and depression-like behaviors via activating the BDNF-TrkB pathway of the striatum

Abstract The circadian rhythm system consists of a master clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus and peripheral clocks dispersed throughout other brain areas (including striatum, Str) as well as various tissues and organs. Circadian rhythm disturbance is a major risk...

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Bibliographic Details

Published in:	Translational Psychiatry
Main Authors:	Xiaotao Liang, Yuewen Ding, Xiaoyu Zhu, Jing Qiu, Xiaoqin Shen, Yifan Xiong, Jieli Zhou, Xiaoshan Liang, Wei Xie
Format:	Article
Language:	English
Published:	Nature Publishing Group 2025-03-01
Online Access:	https://doi.org/10.1038/s41398-025-03313-7