Design, spectral, molecular modeling, antimitotic, analytical and mechanism studies of phenyl isothiocyanate Girard's T derived metal complexes

Abstract The ligand N-{[(phenyl amino) thioxomethyl] hydrazino carbonyl methyl} trimethyl ammonium chloride (PTHAC) was prepared by the refluxing phenyl isothiocyanate and Girard-T (trimethyl ammonium-acethydrazide) in a molar ratio (1:1). The metal complexes derived from NiCl2.6H2O, CuCl2.2H2O and...

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Bibliographic Details

Published in:	BMC Chemistry
Main Authors:	Magda A. Akl, Nora A. El Mahdy, Zizi Elbadrawy, Abdelrahman S. El-Zeny, Mohsen M. Mostafa
Format:	Article
Language:	English
Published:	BMC 2023-11-01
Subjects:	Cu(II) Co(II) Ni(II) Girard-T DFT calculations Molecular docking
Online Access:	https://doi.org/10.1186/s13065-023-01033-x