Ethyl carbamate triggers ferroptosis in liver through inhibiting GSH synthesis and suppressing Nrf2 activation

Humans are inevitably exposed to ethyl carbamate (EC) via consumption of fermented food and beverages. EC, known as an environmental toxin, can cause oxidative stress-mediated severe toxicity, but the underlying mechanisms remain unveiled. Ferroptosis is a newly identified ROS-mediated non-apoptotic...

詳細記述

書誌詳細
出版年:Redox Biology
主要な著者: Yang Xu, Yuting Li, Jiaxin Li, Wei Chen
フォーマット: 論文
言語:英語
出版事項: Elsevier 2022-07-01
主題:
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2213231722001215