Targeting Secreted Protease/Anti-Protease Balance as a Vaccine Strategy against the Helminth <i>Fasciola hepatica</i>

The liver fluke <i>Fasciola hepatica</i> is an economically important global pathogen of humans and their livestock. To facilitate host invasion and migration, <i>F. hepatica</i> secretes an abundance of cathepsin peptidases but prevents excessive damage to both parasite and...

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Bibliographic Details

Published in:	Vaccines
Main Authors:	Krystyna Cwiklinski, Orla Drysdale, Jesús López Corrales, Yolanda Corripio-Miyar, Carolina De Marco Verissimo, Heather Jewhurst, David Smith, Richard Lalor, Tom N. McNeilly, John P. Dalton
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Subjects:	<i>Fasciola hepatica</i> sheep vaccines protease-anti-protease balance stefin Kunitz-type inhibitor
Online Access:	https://www.mdpi.com/2076-393X/10/2/155