Functional protein mining with conformal guarantees

Abstract Molecular structure prediction and homology detection offer promising paths to discovering protein function and evolutionary relationships. However, current approaches lack statistical reliability assurances, limiting their practical utility for selecting proteins for further experimental a...

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Bibliographic Details
Published in:Nature Communications
Main Authors: Ron S. Boger, Seyone Chithrananda, Anastasios N. Angelopoulos, Peter H. Yoon, Michael I. Jordan, Jennifer A. Doudna
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Online Access:https://doi.org/10.1038/s41467-024-55676-y