Samp1 Mislocalization in Emery-Dreifuss Muscular Dystrophy

LMNA linked-Emery-Dreifuss muscular dystrophy (EDMD2) is a rare disease characterized by muscle weakness, muscle wasting, and cardiomyopathy with conduction defects. The mutated protein lamin A/C binds several nuclear envelope components including the Linker of Nucleoskeleton and Cytoskeleton (LINC)...

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Bibliographic Details
Published in:Cells
Main Authors: Elisabetta Mattioli, Marta Columbaro, Mohammed Hakim Jafferali, Elisa Schena, Einar Hallberg, Giovanna Lattanzi
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Subjects:
Emery-Dreifuss Muscular Dystrophy type 2 (EDMD2)
Samp1 (NET5)
prelamin A
LINC complex
myonuclear positioning
Online Access:http://www.mdpi.com/2073-4409/7/10/170

Internet

http://www.mdpi.com/2073-4409/7/10/170

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