Statins as anti‐tumor agents: A paradigm for repurposed drugs

Abstract Background Statins, frequently prescribed medications, work by inhibiting the rate‐limiting enzyme HMG‐CoA reductase (HMGCR) in the mevalonate pathway to reduce cholesterol levels. Due to their multifaceted benefits, statins are being adapted for use as cost‐efficient, safe and effective an...

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書誌詳細

出版年:	Cancer Reports
主要な著者:	Sneha Tripathi, Ekta Gupta, Sanjeev Galande
フォーマット:	論文
言語:	英語
出版事項:	Wiley 2024-05-01
主題:	anti‐cancer drug cholesterol combinatorial therapy drug repurposing lipid metabolism mevalonate pathway
オンライン･アクセス:	https://doi.org/10.1002/cnr2.2078