Biodistribution of etoposide via intratumoral chemotherapy with etoposide-loaded implants

Etoposide (VP16) is the traditional antitumor agent which has been widely used in a variety of cancers. However, intravenous administration of VP16 was limited in clinical application because of its low aqueous solubility, poor bioavailability and dose-limiting adverse effects. Local chemotherapy wi...

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Bibliographic Details

Published in:	Drug Delivery
Main Authors:	Chunsheng Wu, Xiangting Yi, Renzhi Xu, Maokuan Zhang, Yan Xu, Yan Ma, Li Gao, Zhengbao Zha
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2020-01-01
Subjects:	etoposide plla implants intratumoral chemotherapy biodistribution
Online Access:	http://dx.doi.org/10.1080/10717544.2020.1787558