TMEM115: a promising marker for glioma immunotherapy and prognosis

BackgroundGlioma is a common malignant primary brain tumor characterized by a highly immunosuppressive tumor microenvironment and unfavorable prognosis. Transmembrane protein 115 (TMEM115) is a protein-coding gene. It may play a role in the retrograde transport of proteins from the Golgi to the endo...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Hang Yin, Feng Wang, Haiyan Xu, Manyu Xu, Pengpeng Lu, Xiaojing Zhang, Lei Yang, Bing Lu, Pingping Sun, Jianfei Huang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-06-01
Subjects:	glioma TMEM115 prognosis M2 macrophage PD-L1
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1598499/full