Identifying cell states in single-cell RNA-seq data at statistically maximal resolution.

Single-cell RNA sequencing (scRNA-seq) has become a popular experimental method to study variation of gene expression within a population of cells. However, obtaining an accurate picture of the diversity of distinct gene expression states that are present in a given dataset is highly challenging bec...

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Bibliographic Details
Published in:PLoS Computational Biology
Main Authors: Pascal Grobecker, Thomas Sakoparnig, Erik van Nimwegen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-07-01
Online Access:https://doi.org/10.1371/journal.pcbi.1012224