Concomitant autoimmunity and late cancers in adult-onset immunodeficiency due to neutralizing anti-IFN-γ autoantibodies

BackgroundOpportunistic intramacrophagic infections are well-characterized in adult-onset immunodeficiency associated with neutralizing anti-IFN-γ autoantibodies (nAIGA).ObjectiveConcomitant autoimmune and neoplastic diseases are rarely described.MethodsThis study included 50 patients diagnosed with...

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Bibliographic Details

Published in:	Frontiers in Immunology
Main Authors:	Wan-Ting Tsai, Chih-Yun Cheng, Hsin-Yun Sun, Bei-Chia Guo, Ying-Chieh Chiang, Chiao-Feng Cheng, Yi-Hua Pan, Un-In Wu, Jann-Tay Wang, Wang-Huei Sheng, Aristine Cheng, Yee-Chun Chen, Shan-Chwen Chang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Subjects:	anti-interferon-γ autoantibody autoimmunity secondary immunodeficiency urothelial carcinoma papillary thyroid carcinoma autoimmune thyroiditis
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1526439/full