Nanoalum Formulations Containing Aluminum Hydroxide and CpG 1018^TM Adjuvants: The Effect on Stability and Immunogenicity of a Recombinant SARS-CoV-2 RBD Antigen

Aluminum-salt vaccine adjuvants (alum) are commercially available as micron-sized particles with varying chemical composition and crystallinity. There are reports of enhanced adjuvanticity when the alum’s particle size is reduced to the nanometer range. Previously, we demonstrated that a recombinant...

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出版年:	Vaccines
主要な著者:	Sakshi Bajoria, Ozan S. Kumru, Jennifer Doering, Katherine Berman, Greta Van Slyke, Anneka Prigodich, Sergio A. Rodriguez-Aponte, Harry Kleanthous, J. Christopher Love, Nicholas J. Mantis, Sangeeta B. Joshi, David B. Volkin
フォーマット:	論文
言語:	英語
出版事項:	MDPI AG 2023-05-01
主題:	nanoalum CpG 1018 adjuvant nanoparticle vaccine formulation
オンライン･アクセス:	https://www.mdpi.com/2076-393X/11/6/1030