Impact of Extended Dosing Intervals and Ipsilateral Versus Contralateral Boosting on mRNA Vaccine Immunogenicity in Mice

Background: Although mRNA vaccines have the potential to be developed and deployed rapidly to combat infectious diseases, the ideal method of administration and boosting schedule strategy for generating optimal immunogenicity is an area of active research. We compared the immune responses resulting...

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Bibliographic Details

Published in:	Vaccines
Main Authors:	Bin Lu, Omkar Chaudhary, Balaji Banoth, Janhavi Nadkarni, Wei Zong, Emilie Mausser, Hillary Danz, Mona Motwani, Sophie Ruiz, Donghui Zhang, Gopinath Nageshwaran, Bachra Rokbi, William Warren, Frank DeRosa, Sudha Chivukula
Format:	Article
Language:	English
Published:	MDPI AG 2025-03-01
Subjects:	mRNA-LNP vaccines influenza ipsilateral contralateral prime–boost interval
Online Access:	https://www.mdpi.com/2076-393X/13/3/263