Clinical Characterization of a National Cohort of Patients With Germline WT1 Variants Including Late-Onset Phenotypes

Introduction: WT1 disorder is a recently introduced term for phenotypes associated with germline Wilms Tumor 1 (WT1) variants, including glomerulopathy, urogenital anomalies, and Wilms tumor. Previous studies showed a bias toward missense variants in the DNA-binding/Zinc-finger domain of WT1 (exon 8...

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Bibliographic Details

Published in:	Kidney International Reports
Main Authors:	Sophie E. van Peer, Roland P. Kuiper, Janna A. Hol, Sanne Egging, Bert van der Zwaag, Marc R. Lilien, M. Paola Lombardi, Marry M. van den Heuvel-Eibrink, Marjolijn C.J. Jongmans
Format:	Article
Language:	English
Published:	Elsevier 2024-12-01
Subjects:	Denys-Drash Wilms tumor WT1
Online Access:	http://www.sciencedirect.com/science/article/pii/S2468024924019259