Partially brain effects of injection of human umbilical cord mesenchymal stem cells at injury sites in a mouse model of thoracic spinal cord contusion

PurposeThe pain caused by spinal cord injury (SCI) poses a major burden on patients, and pain management is becoming a focus of treatment. Few reports have described changes in the brain after SCI. Particularly, the exact mechanism through which brain regions affect post-injury pain remains unclear....

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Bibliographic Details

Published in:	Frontiers in Molecular Neuroscience
Main Authors:	Haijun Hu, Houqing Long, Zhenxiao Ren, Tianhua Liu, Jinghui Xu, Fan Xiao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Subjects:	spinal cord injury (SCI) contusion human umbilical cord mesenchymal stem cells (hu-MSCs) anterior cingulate cortex (ACC) periaqueductal gray (PAG) neurogenic pain
Online Access:	https://www.frontiersin.org/articles/10.3389/fnmol.2023.1179175/full