Drugs Targeting Sirtuin 2 Exhibit Broad-Spectrum Anti-Infective Activity

Direct-acting anti-infective drugs target pathogen-coded gene products and are a highly successful therapeutic paradigm. However, they generally target a single pathogen or family of pathogens, and the targeted organisms can readily evolve resistance. Host-targeted agents can overcome these limitati...

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發表在:	Pharmaceuticals
Main Authors:	Thomas Shenk, John L. Kulp III, Lillian W. Chiang
格式:	Article
語言:	英语
出版:	MDPI AG 2024-09-01
主題:	SIRT1 SIRT2 sirtuin host-targeted agents antiviral anti-infective
在線閱讀:	https://www.mdpi.com/1424-8247/17/10/1298