The impact of mild episodic ketosis on microglia and hippocampal long‐term depression in 5xFAD mice

Abstract Ketotherapeutics is a potential metabolic intervention for mitigating dementias; however, its mechanisms and optimal methods of application are not well understood. Our previous in vitro study showed that β‐hydroxybutyrate (BHB), a major ketone body, reverses pathological features of amyloi...

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Bibliographic Details
Published in:FASEB BioAdvances
Main Authors: Jacopo Di Lucente, Jon J. Ramsey, Lee‐Way Jin, Izumi Maezawa
Format: Article
Language:English
Published: Wiley 2024-12-01
Subjects:
Online Access:https://doi.org/10.1096/fba.2024-00123