Identification of a neutralizing epitope within minor repeat region of Plasmodium falciparum CS protein

Abstract Malaria remains a major cause of morbidity and mortality worldwide with 219 million infections and 435,000 deaths predominantly in Africa. The infective Plasmodium sporozoite is the target of a potent humoral immune response that can protect murine, simian and human hosts against challenge...

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Bibliographic Details
Published in:npj Vaccines
Main Authors: J. Mauricio Calvo-Calle, Robert Mitchell, Rita Altszuler, Caroline Othoro, Elizabeth Nardin
Format: Article
Language:English
Published: Nature Portfolio 2021-01-01
Online Access:https://doi.org/10.1038/s41541-020-00272-6