Factor XIII is a newly identified binding partner for platelet collagen receptor GPVI‐dimer—An interaction that may modulate fibrin crosslinking

Abstract Background In the fibrin‐forming process, thrombin cleaves fibrinogen to fibrin, which form fibrils and then fibers, producing a gel‐like clot. Thrombin also activates coagulation factor XIII (FXIII), which crosslinks fibrin γ‐chains and α‐chains, stabilizing the clot. Many proteins bind to...

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Bibliographic Details

Published in:	Research and Practice in Thrombosis and Haemostasis
Main Authors:	Masaaki Moroi, Isuru Induruwa, Richard W. Farndale, Stephanie M. Jung
Format:	Article
Language:	English
Published:	Elsevier 2022-03-01
Subjects:	crosslinking factor XIII fibrin fibrin clot GPVI GPVI‐dimer
Online Access:	https://doi.org/10.1002/rth2.12697